Licorice hka ja ai: N-gup hte sha ai "Super-Photon" Licochalcone A hpe hpraw hkra galaw na matu hpaji masa hku nna hpaw ya ai

"Fair skin gaw n kaja ai lam latsa hpe makoi da ya ai; dark skin gaw yawng hpe jahten kau ya ai."

N-gup tsawm htap ai arung arai ni a matu mungkan ting na madung gat lawk langai hku nna, Miwa mungdan a gat lawk gaw 100 daram du wa na re ngu sawn la ma ai.2025 ning hta RMB wan 25.57, mungkan hta kaba dik htum gat lawk byin tai wa na matu rawt jat wa ai hte .3.8% shaning shagu rawt jat galu kaba wa ai.
Miwa mungdan a n-gup tsawm htap ai daw kata hta,hpraw ai hpan gaw kaba wa ai rawt jat lam hpe hkam sha nga ai. Ga shadawn, JD.com kaw 1990 ning hta.2025 a shawng na mali ning laman(Sumla 1),SKU nnan 3,500 janhpraw hkra galaw ai daw- hta hpaw hpang wa sai.n-gup tsawm htap ai arung arai nnan yawng hta na 90% daram hpe hkam la aidai aten laman hta, kaga sub-category ni rai nga ai, asak kaba wa ai hpe ninghkap ai, hka jaw ai, hte -sam n-gun yawm ai hpe ninghkap ai [1] ni hta grau law ai [1].

Hpraw hkra galaw ai arung arai ni hpe grai sawng ai hku garan ginhka ai lam-Actives nnan ni hpe lawan ladan ra nga ai

Ya aten hta gat lawk hta nga ai n-gup hpe hpraw hkra galaw ai madung arung arai ni gaw .glutashion, Ergothionein, Htehpraw ai hkaulan mam ntsin. Shawng na lahkawng gaw madung hku nna shanhte a tsun shadut ai lam hpe .n-gun n rawng ai hte n-gun rawng ai radical ni hpe yeng seng kau ya ai, hpang jahtum na gaw shi a .nhtoi hpe makawp maga aiakyu ara ni hpe lu la ai (Table 1).

Raitim, size shagu na brand ni gaw concept fatigue hpe hkrum sha nga ai. Whitening products ni gaw ingredient lata ai lam hta grau grau bung wa ai majaw, ndai bai kahtap tsun ai manu jahpu ni hpe mari ai ni myit n lawm mat wa ai. Gat lawk hta lawan ladan ra kadawn nga ai.n-gup hpraw hkra galaw ai actives nnan nin shamu n shamawt nga ai n-gup tsawm htap ai lam hta n-gun nnan bang na matu.

Ndai hpyi shawn ai lam a mahtai gaw .mawn sumli hpan.

"Cosmetics–food homology" ngu ai masa rawt jat wa ai hte maren, hkum hkrang nsam hpe yu lajang ai lam hta, n-gup tsawm htap ai lam a matu, masha law law ra sharawng ai arung arai ni a ningmu ni hpe shabyin ya sai.ErgothioneinHelena Rubinstein a hkrang sumla kaw nna hpang wa aiHpraw ai shingkyitcream (Sumla 2) hpe Later Lift gaw shi a "Ice Crystal Skin" ngu ai n-gup hte sha ai tsi mawan de galai shai kau ai (Sumla 3). ngu ai myit masa hpe .AstaxanthinPROYA kaw na pru wa aiLahkawng lang Antiline (Sumla 4), dai hpang Me Today a .Htoi htoi tu ai(Hkrang 5).

Hpang na byin mai ai shagan ingredient,n-gup magap, Guyu kaw na pru wa ai .Aurora hkaulan mamseries (Sumla 6) hpe hti yu ga. Ndai hpraw ai line gaw glabridin hpe madung tawn nna, Guyu hpe 1000 hpe lu la hkra karum ya ai.GMV hta RMB wan 5. Miwa mungdan a glabridin grup yin hta gawgap da ai ningbaw ningla skincare brand langai hku nna, Guyu gaw PROYA hte Kans zawn re ai mungdan kata na brand ni hpe grau nna lai di nna, n-gun ja ai rawt jat lam hpe madun dan sai.

Raitim, mungdan kata hta gaw .n-gup tsawm htap aisector, glabridin gaw law malawng n jai lang shi ai-n-gup tsawm htap ai brand ni a matu ahkyak ai ahkaw ahkang nnan hpe shabyin ya nga ai.

Hkrang 2 & 3: Helena Rubinstein a hpraw ai shingkyit hte hpang e hka lim ai hkum hkrang hpe sharawt ai (ergothioneine lawm ai)

Hkrang 4 & 5: PROYA Lahkawng lang Anti hte Ngai Dai ni Htoi Hpe Hkrang (astaxanthin lawm ai)

Hkrang 6: Guyu Aurora hka htung (glabridin hte galaw da ai)

Hkum hkrang hpraw hkra galaw ai Licorice a ladat ni

Licorice gaw Miwa mung hta lusha hte tsi mawan lahkawng yan hta lang ai labau galu nga ai rai nna, .dual-lang ai malu masha–tsin-gun dat. Miwa htunghking tsawm htap ai ladat hta"San Bai Gan Cao Tang", licorice hpe Atractylodes, White Peony, Poria ni hte kayau nna, hkum hkrang nsam grai law ai, nsam nsam nsam nsam, nsam nsam nsam nsam, nsam hpraw ai zawn re ai ni hpe n-gun jaw ai. Licorice hpe mung -chye da ai htunghking hku hpraw hkra galaw ai tsi ni hta lawm ai ."Yu Rong San"Hte"Yu Nu Tao Hua Fen."

Dai ni na aten na sawk sagawn ai lam ni hta, licorice hta bioactive n-gun rawng ai arung arai ni lawm ai hpe mu lu ai.glisarizin, Glisirretinik asid, Hten-gup magap, dai gaw nhtoi htoi ai, oxidative stress, hte n-gun ja ai stimuli ni hpe hkrum katut ai melanocytes ni hpe kaja ai hku shadut ya nna, melanin grai law hkra byin pru wa na masa hpe shayawm ya ai. Dai hta n-ga, licorice gaw melanin hpe 1000 hku nna shayawm ya lu ai.Tyrosinase hpe pat shingdang ai, nsam hpraw ai hta lawm ai madung enzyme re.

"N-gup hta grai kaja ai nhtoi" - Glabridin

Licorice amyu law law nga ai, Miwa mung hta lang na matu masum hpe ahkang jaw da ai:Glycyrhiza uralensis, Glycyrrhiza n-gun rawng ai, HteGlycyrhiza glabra. Glabridin, laklai ai bioactive compound hpe 1990 ning hta sha mu lu ai.Glycyrhiza glabra, hpe shinggyin la na matu shaning law law rawt jat ra ai rai nna, grai npu madang hta shingra tara hku nna nga ai.
Kaw nnaG. glabra hpun ni hpe kg 1,000 ., sha0.1 kg daram glabridinshi a rarity hpe madi madun ai 1:10,000 shaw la ai ratio hpe shaw la mai ai-.

Dai aten hta sha, glabridin gaw .mau hpa n-gun ja ai hpraw shangun ai atsam, ngu ai mying hpe lu la ai ."n-gup na super photonic" arung arai. Skincare sector hta grai htuk manu wa sai rai nna, beauty brand kaba ni mung grai hkap la nga ai.

Atsam rawng ai Tyrosinase hpe pat shingdang ai tsi langai mi**

Antioxidant hte anti-hkum hkrang n-gun shayawm ai atsam ni hta lai nna, glabridin a laklai ai magam bungli gaw shi a .Tyrosinase hpe n-gun ja ai hku pat shingdang ai atsam. Chye da ai shingra hpun - kaw na pru wa ai actives yawng hta, shi hta shingjawng ai n law ai, shi a pat shingdang ai atsam gaw 100 rai nga ai.grai tsaw ai1990 ning hta, n-gun ja ai tyrosinase hpe pat shingdang ai tsi ni hta grau nnakojik asidHteArbutin.

Shapraw da ai sawk sagawn ai lam [2] hku nga yang, glabridin gaw .molecular chyinghka-hkum, tyrosinase a catalytic center de shang na matu pat shingdang da ai. Tyrosine hpe active site de n shang hkra pat shingdang nna, hpang e galai shai wa ai hpe pat shingdang ai hku nna, glabridin gaw kaja wa .shi a npawt nhpang kaw na melanin byin pru wa ai hpe jahkring kau ya ai.

Hkrang 8:
A: Glabridin n nga ai shaloi, tyrosine (hpraw nsam hpraw) gaw, n-gun dat hpe n-gun dat dat ai shara de shang wa nna, kalang ta melanin de galai shai mat wa ai.
B: Glabridin (hpraw nsam hpraw) nga ai shara hta, catalytic center de shang wa ai chyinghka hpe pat da ai majaw, tyrosine n shang wa lu ai.

Masum ngu na-hpung langai kaw na chyam dinglik ai jahpan hku yu yang [4], Licochalcone A hte LicoSnow licorice ntsin a tyrosinase hpe pat shingdang ai atsam gaw, dai hte bung ai arung arai ni hta grau kaja ai. Ndai chyam dinglik ai lam hta, tyrosinase a daw mi-maximal pat shingdang ai n-gun (IC50) hpe jep joi ai lam hta jai lang ai. Ndai masat kumla gaw tyrosinase magam bungli hpe 50% pat shingdang na matu ra ai raw material a n-gun hpe madi madun ai. IC50 manu n law ai gaw, raw material gaw n law ai n-gun hta grai ahkyak ai pat shingdang ai lam ni hpe madun dan ai, grau n-gun ja ai tyrosinase pat shingdang ai lam hpe madun dan ai.

Tara rap ra ai lam hpe kam na matu, ndai chyam dinglik ai lam hpe shingdaw ai hpung lahkawng hku garan nna galaw ai:

Hpung 1: High-purity raw materials (purity >98%), Licochalcone A, glutathione, ergothioneine, hte kojic acid (tyrosinase hpe pat shingdang na matu kaja ai hkang ai lam) lawm ai, yawng rai yang, arung arai mali lawm ai.

Hpung 2:Hpun kaw na prut prut ai arai ni, LicoSnow hkaulan mam ntsin (4% Licochalcone A lawm ai), melon hkaulan mam ntsin (SOD lawm ai), hkaulan mam hpraw ntsin (dihydro{1}}/tetrahydro{2}}lycopene lawm ai) ni lawm ai, yawng rai yang, arung arai masum lawm ai.

Raw material langai hpra a IC50 manu ni hpe Table 2 hta madun da ai.

IC50 manu ni hpe madung tawn nna, shingdaw yu yang, hpung lahkawng a tyrosinase hpe pat shingdang ai atsam hpe sumla 9 hte 10 hta madun da ai.Hpung 1 hta, Licochalcone A a tyrosinase hpe pat shingdang ai atsam gaw glutathione a htam 1.4, kojic acid times a htam 3,14 htam grau law ai. Group 2 hta, LicoSnow licorice hka htung a tyrosinase hpe pat shingdang ai atsam gaw, melon hka htung hta na htam 11, hkaulan mam hpraw hka htung hta na htam 6,930 daram law ai.

Licorice hte n-gup hpraw hkra galaw ai hpe tsi rung kaw na jep joi ai lam

Licochalcone A a hpraw hkra galaw ya ai atsam hpe hpaji ninghkring ni chye na da ai aten na sai rai nna, hkum hkrang nsam hpe yu lajang ai lam hta manu shadan ai lam grau grau law wa ai raitim, n-gup hpraw hkra galaw ya ai atsam hte seng nna, shinggyim masha ni a tsi gawk hta sawk sagawn ai lam ni hpe shapraw ai lam n nga ai. LicoSnow hkaulan mam ntsin (4% Licochalcone A lawm ai) gaw ndai n-gun hpe hkrak sha jahpring ya ai.

Huasheng Ingredients gaw, mying kaba ai third-party chyam dinglik hpung langai hte pawng nna, shata 1-shinggyim masha marai 34 (asak 25–50 ning lapran na num ni) hpe chyam dinglik ai lam galaw ai [5]. Shang lawm ai ni gaw, LicoSnow hkaulan mam ntsin hpe lani mi hta 100 mg (Licochalcone A 4 mg lawm ai) hpe n-gup hku sha ai. Whitening effects hpe instrument hpe madung tawn nna shadawn shadang hte ga san laika ni hku nna jep joi ai lam galaw ai. Chyam dinglik ai lam a mahtai gaw lawu na hte maren rai nga ai.

Myi man nsam hpe shayawm ya ai (16%↓):
Nhtoi 28 ya tup lu sha ngut ai hpang, myi man nsam nsam rawng ai shara gaw 19.87% kaw nna 16.65% de yawm mat wa ai, 16.21% yawm mat ai (p=0.004), dai gaw n-gun n rawng ai aten hte n-gun rawng ai hpang grai shai hkat ai hpe madun ai. Shanglawm ai ni a myi man nsam hpe shingdaw yu ai hpe sumla 11 hta madun da ai.

Hkrang 11: Myi man nsam galai shai ai lam; left: n sha shi yang, right: sha ngut ai hpang

Hkum hkrang nsam htoi tu ai lam law wa ai (21%↑):
nhtoi na ai hpang, myi man nsam htoi tu ai gaw 4.0% kaw nna 4.84% de jat wa nna, 21.00% rawt jat wa ai (p=0.014), n-gun jat ai shawng hte n-gun jat ai hpang hta grai shai hkat ai hpe madun ai. Shanglawm ai ni a hkum hkrang nsam hpe shingdaw yu ai hpe sumla 12 hta madun da ai.

Hkrang 12: Myi man a nsam galai shai ai lam; left: n sha shi yang, right: sha ngut ai hpang

-UV nsam hpe shayawm ai (15%↓):
Shang lawm ai ni a shingdu de artificial UV irradiation hpe bang nna, nsam hpraw ai shara ni hpe galaw ai. Irradiation galaw ngut ai hpang lahkawng ya na ai hpang, post-UV nsam hpe jep joi na matu, nsam garan ai lam hpe shadawn ai. Shadawn shadang ni hpe n-gun jat bang hpang ai aten (D-2 nhtoi htoi ai, D0 shadawn ai) hte jahtum (D28 nhtoi htoi ai, D30 shadawn ai) hta shadawn ai. nhtoi na ai hpang, tan galaw da ai shara ni hta melanin manu ni gaw 99 kaw nna 84 de yawm mat wa ai, 15.15% (p < 0.001) yawm mat wa ai, dai gaw n-gun jat ai shawng hte n-gun jat ai hpang hta grai shai hkat ai hpe madun ai.

Hkum hkrang nsam hpraw ai hpe shayawm ya ai (28%↓):
nhtoi na ai hpang, shingdu maga na hpraw ai manu (a* manu, grau tsaw ai manu ni gaw grau hpraw ai hkum hkrang hpe madun ai) gaw 10.70 kaw nna 7.69 de yawm mat wa ai, 28.13% (p < 0.001) yawm mat wa ai, dai gaw n-gun jat ai shawng hte n-gun jat ai hpang hta grai shai hkat ai hpe madun ai.

Yawng hkra hkum hkrang hpe gram lajang ai lam (≈90% shanglawm ai ni myit hkrum ai):
nhtoi na ai hpang, shanglawm ai ni hta na 90% daram gaw, hkum hkrang yawng hta grau kaja wa ai lam tsun dan ai, hkum hkrang nsam grau htoi tu wa ai, nsam htoi tu wa ai, nsam hpraw ai (sh) nsam hpraw ai hpe shayawm ya ai zawn re ai lam ni hpe tsun dan ai.

Kaja ai shimlam masa:
Chyam dinglik ai aten laman hta n kaja ai akyu n mu lu ai.

Laika buk ni:
[1] Boguang sawk sagawn hpung kaw nna galaw ai.2025 Miwa Mungdan N-gup Hpaji Hpaji Hkringmang Dap a gat lawk sawk sagawn ai shiga.
[2] Chen J, Yu X, Huang Y.Glabridin a n-gun hpe pat shingdang ai ladat ni.168:111-117. Nov 5;168:111-117.
[3] Shenzhen 863 Chyam dinglik rung kaw nna shapraw ai chyam dinglik shiga.
[4] Huace Testing kaw nna shapraw ai shinggyim masha ni hpe chyam dinglik ai shiga.